Nucleosomes influence multiple steps during replication initiation

Nucleosomes influence multiple steps during replication initiation

Eukaryotic replication origin licensing, activation and timing are influenced by chromatin but a mechanistic understanding is lacking. Using reconstituted nucleosomal DNA replication assays, we assessed the impact of nucleosomes on replication initiation. To generate distinct nucleosomal landscapes,...

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Bibliographic Details
Main Authors: Watanabe, Shinya (Author), Kang, Sukhyun (Author), Belsky, Jason A (Author), MacAlpine, David M. (Author), Peterson, Craig L (Author), Azmi, Ishara F (Contributor), Maloney, Michael Finnan (Contributor), Bell, Stephen P (Contributor)
Other Authors: Massachusetts Institute of Technology. Department of Biology (Contributor)
Format: Article
Language:English
Published: eLife Sciences Publications, Ltd., 2017-06-13T18:55:37Z.
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