Hyper- and hypo- nutrition studies of the hepatic transcriptome and epigenome suggest that PPARα regulates anaerobic glycolysis

Hyper- and hypo- nutrition studies of the hepatic transcriptome and epigenome suggest that PPARα regulates anaerobic glycolysis

Diet plays a crucial role in shaping human health and disease. Diets promoting obesity and insulin resistance can lead to severe metabolic diseases, while calorie-restricted (CR) diets can improve health and extend lifespan. In this work, we fed mice either a chow diet (CD), a 16 week high-fat diet...

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Main Authors: Vernia, Santiago (Author), Kennedy, Norman J. (Author), Davis, Roger J. (Author), Soltis, Anthony Robert (Contributor), Motola, Shmulik (Contributor), Ng, Christopher W. (Contributor), Dalin, Simona (Contributor), Matthews, Bryan (Contributor), Fraenkel, Ernest (Contributor)
Other Authors: Massachusetts Institute of Technology. Department of Biological Engineering (Contributor)
Format: Article
Language:English
Published: Nature Publishing Group, 2017-06-20T15:20:39Z.
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