Polymeric mechanical amplifiers of immune cytokine-mediated apoptosis

Polymeric mechanical amplifiers of immune cytokine-mediated apoptosis

Physical forces affect tumour growth, progression and metastasis. Here, we develop polymeric mechanical amplifiers that exploit in vitro and in vivo physical forces to increase immune cytokine-mediated tumour cell apoptosis. Mechanical amplifiers, consisting of biodegradable polymeric particles teth...

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Bibliographic Details
Main Authors: Mitchell, Michael J (Contributor), Webster, Jamie (Contributor), Chung, Amanda T (Contributor), Guimaraes, Pedro P G (Contributor), Khan, Omar Fizal (Contributor), Langer, Robert S (Contributor)
Other Authors: Massachusetts Institute of Technology. Department of Biological Engineering (Contributor), Massachusetts Institute of Technology. Department of Chemical Engineering (Contributor), Koch Institute for Integrative Cancer Research at MIT (Contributor)
Format: Article
Language:English
Published: Nature Publishing Group, 2017-06-20T17:43:48Z.
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