An inter-residue network model to identify mutational-constrained regions on the Ebola coat glycoprotein

An inter-residue network model to identify mutational-constrained regions on the Ebola coat glycoprotein

Recently, progress has been made in the development of vaccines and monoclonal antibody cocktails that target the Ebola coat glycoprotein (GP). Based on the mutation rates for Ebola virus given its natural sequence evolution, these treatment strategies are likely to impose additional selection press...

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Bibliographic Details
Main Authors: Quinlan, Devin Scott (Contributor), Raman, Rahul (Contributor), Tharakaraman, Kannan (Contributor), Subramanian, Vidya (Contributor), del Hierro, Gabriella A. (Contributor), Sasisekharan, Ram (Contributor)
Other Authors: Harvard University- (Contributor), Massachusetts Institute of Technology. Department of Biological Engineering (Contributor), Massachusetts Institute of Technology. Department of Chemical Engineering (Contributor)
Format: Article
Language:English
Published: Nature Publishing Group, 2017-06-21T13:14:50Z.
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