Argonaute-Bound Small RNAs from Promoter-Proximal RNA Polymerase II

Argonaute-Bound Small RNAs from Promoter-Proximal RNA Polymerase II

Argonaute (Ago) proteins mediate posttranscriptional gene repression by binding guide miRNAs to regulate targeted RNAs. To confidently assess Ago-bound small RNAs, we adapted a mouse embryonic stem cell system to express a single epitope-tagged Ago protein family member in an inducible manner. Here,...

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Bibliographic Details
Main Authors: Zamudio, Jesse Ray (Contributor), Kelly, Timothy James (Contributor), Sharp, Phillip A. (Contributor)
Other Authors: Massachusetts Institute of Technology. Department of Biology (Contributor), Koch Institute for Integrative Cancer Research at MIT (Contributor)
Format: Article
Language:English
Published: Elsevier, 2017-06-27T18:42:04Z.
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