Crystallographic Evidence of Drastic Conformational Changes in the Active Site of a Flavin-Dependent

The soil actinomycete Kutzneria sp. 744 produces a class of highly decorated hexadepsipeptides, which represent a new chemical scaffold that has both antimicrobial and antifungal properties. These natural products, known as kutznerides, are created via nonribosomal peptide synthesis using various de...

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Bibliographic Details
Main Authors: Heemstra, John R. (Author), Walsh, Christopher T. (Author), Setser, Jeremy Wayne (Contributor), Drennan, Catherine L. (Contributor)
Format: Article
Language:English
Published: American Chemical Society (ACS), 2017-07-05T17:51:16Z.
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