Active chromatin and transcription play a key role in chromosome partitioning into topologically associating domains

Active chromatin and transcription play a key role in chromosome partitioning into topologically associating domains

Recent advances enabled by the Hi-C technique have unraveled many principles of chromosomal folding that were subsequently linked to disease and gene regulation. In particular, Hi-C revealed that chromosomes of animals are organized into topologically associating domains (TADs), evolutionary conserv...

Full description

Bibliographic Details
Main Authors: Ulianov, Sergey V. (Author), Khrameeva, Ekaterina E. (Author), Gavrilov, Alexey A. (Author), Flyamer, Ilya M. (Author), Kos, Pavel (Author), Mikhaleva, Elena A. (Author), Penin, Aleksey A. (Author), Logacheva, Maria D. (Author), Chertovich, Alexander (Author), Gelfand, Mikhail S. (Author), Shevelyov, Yuri Y. (Author), Razin, Sergey V. (Author), Imakaev, Maksim Viktorovich (Contributor)
Other Authors: Massachusetts Institute of Technology. Department of Physics (Contributor)
Format: Article
Language:English
Published: Cold Spring Harbor Laboratory Press, 2017-07-07T14:24:59Z.
Subjects:
Article
Online Access:Get fulltext

Internet

Get fulltext

Similar Items