Defining the Minimal Factors Required for Erythropoiesis through Direct Lineage Conversion

Defining the Minimal Factors Required for Erythropoiesis through Direct Lineage Conversion

Erythroid cell commitment and differentiation proceed through activation of a lineage-restricted transcriptional network orchestrated by a group of well characterized genes. However, the minimal set of factors necessary for instructing red blood cell (RBC) development remains undefined. We employed...

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Main Authors: Capellera-Garcia, Sandra (Author), Pulecio, Julian (Author), Dhulipala, Kishori (Author), Siva, Kavitha (Author), Rayon-Estrada, Violeta (Author), Singbrant, Sofie (Author), Sommarin, Mikael N.E (Author), Walkley, Carl R (Author), Soneji, Shamit (Author), Karlsson, Göran (Author), Raya, Ángel (Author), Flygare, Johan (Author), Sankaran, Vijay G. (Contributor)
Other Authors: Broad Institute of MIT and Harvard (Contributor)
Format: Article
Language:English
Published: Elsevier, 2017-07-10T14:39:24Z.
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