Highly Parallel Genome-wide Expression Profiling of Individual Cells Using Nanoliter Droplets

Highly Parallel Genome-wide Expression Profiling of Individual Cells Using Nanoliter Droplets

Cells, the basic units of biological structure and function, vary broadly in type and state. Single-cell genomics can characterize cell identity and function, but limitations of ease and scale have prevented its broad application. Here we describe Drop-seq, a strategy for quickly profiling thousands...

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Bibliographic Details
Main Authors: Macosko, Evan Z (Author), Satija, Rahul (Author), Nemesh, James (Author), Shekhar, Karthik (Author), Goldman, Melissa (Author), Tirosh, Itay (Author), Bialas, Allison R (Author), Kamitaki, Nolan (Author), Martersteck, Emily M (Author), Trombetta, John J (Author), Weitz, David A (Author), Sanes, Joshua R (Author), McCarroll, Steven A (Author), Shalek, Alexander K (Contributor), Regev, Aviv (Contributor), Basu, Anindita 1978- (Author)
Other Authors: Institute for Medical Engineering and Science (Contributor), Massachusetts Institute of Technology. Department of Biology (Contributor), Massachusetts Institute of Technology. Department of Chemistry (Contributor)
Format: Article
Language:English
Published: Elsevier, 2017-07-10T19:17:28Z.
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