Unrestrained AMPylation targets cytosolic chaperones and activates the heat shock response

Protein AMPylation is a conserved posttranslational modification with emerging roles in endoplasmic reticulum homeostasis. However, the range of substrates and cell biological consequences of AMPylation remain poorly defined. We expressed human and Caenorhabditis elegans AMPylation enzymes-huntingti...

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Bibliographic Details
Main Authors: Truttmann, Matthias C. (Author), Zheng, Xu (Author), Hanke, Leo (Author), Damon, Jadyn R. (Author), Grootveld, Monique (Author), Krakowiak, Joanna (Author), Pincus, David (Author), Ploegh, Hidde (Contributor)
Other Authors: Massachusetts Institute of Technology. Department of Biology (Contributor)
Format: Article
Language:English
Published: National Academy of Sciences (U.S.), 2017-09-13T19:50:57Z.
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