Pathogen boosted adoptive cell transfer immunotherapy to treat solid tumors

Pathogen boosted adoptive cell transfer immunotherapy to treat solid tumors

Because of insufficient migration and antitumor function of transferred T cells, especially inside the immunosuppressive tumor microenvironment (TME), the efficacy of adoptive cell transfer (ACT) is much curtailed in treating solid tumors. To overcome these challenges, we sought to reenergize ACT (R...

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Bibliographic Details
Main Authors: Xin, Gang (Author), Schauder, David M. (Author), Jing, Weiqing (Author), Jiang, Aimin (Author), Johnson, Bryon (Author), Cui, Weiguo (Author), Joshi, Nik (Author)
Other Authors: Koch Institute for Integrative Cancer Research at MIT (Contributor), Joshi, Nikhil (Contributor)
Format: Article
Language:English
Published: National Academy of Sciences (U.S.), 2017-09-14T20:00:35Z.
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