Enriched Protein Screening of Human Bone Marrow Mesenchymal Stromal Cell Secretions Reveals MFAP5 and PENK as Novel IL-10 Modulators

Enriched Protein Screening of Human Bone Marrow Mesenchymal Stromal Cell Secretions Reveals MFAP5 and PENK as Novel IL-10 Modulators

The secreted proteins from a cell constitute a natural biologic library that can offer significant insight into human health and disease. Discovering new secreted proteins from cells is bounded by the limitations of traditional separation and detection tools to physically fractionate and analyze sam...

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Bibliographic Details
Main Authors: Elman, Jessica S (Author), Shen, Keyue (Author), Gabow, Aaron (Author), Yarmush, Joshua (Author), Jiao, Yunxin (Author), Fletcher, Anne (Author), Lee, Jungwoo (Author), Yarmush, Martin L (Author), Parekkadan, Biju (Author), Li, Matthew (Contributor), Manrai, Arjun Kumar (Contributor), Milwid, Jack (Author), Cima, Michael J. (Author)
Other Authors: Harvard University- (Contributor), Massachusetts Institute of Technology. Department of Materials Science and Engineering (Contributor), Koch Institute for Integrative Cancer Research at MIT (Contributor), Milwid, Jack Miles (Contributor), Cima, Michael J (Contributor)
Format: Article
Language:English
Published: Elsevier BV, 2017-10-05T17:15:39Z.
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