The guanine-nucleotide exchange factor CalDAG GEFI fine-tunes functional properties of regulatory T cells

The guanine-nucleotide exchange factor CalDAG GEFI fine-tunes functional properties of regulatory T cells

Using quantitative phosphopeptide sequencing of unstimulated versus stimulated primary murine Foxp3(+) regulatory and Foxp3(-) conventional T cells (Tregs and Tconv, respectively), we detected a novel and differentially regulated tyrosine phosphorylation site within the C1 domain of the guanine-nucl...

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Main Authors: Niemz, Jana (Author), Kliche, Stefanie (Author), Pils, Marina C. (Author), Morrison, Eliot (Author), Manns, Annika (Author), Freund, Christian (Author), Galla, Melanie (Author), Jänsch, Lothar (Author), Huehn, Jochen (Author), Crittenden, Jill R (Contributor), Graybiel, Ann M (Contributor)
Other Authors: Massachusetts Institute of Technology. Department of Brain and Cognitive Sciences (Contributor), McGovern Institute for Brain Research at MIT (Contributor)
Format: Article
Language:English
Published: Akademiai Kiado RT, 2017-11-14T18:44:09Z.
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