Pathogenic Huntington Alters BMP Signaling and Synaptic Growth through Local Disruptions of Endosomal Compartments
Huntington's disease (HD) is a neurodegenerative disorder caused by expansion of a polyglutamine (polyQ) stretch within the Huntingtin (Htt) protein. Pathogenic Htt disrupts multiple neuronal processes, including gene expression, axonal trafficking, proteasome and mitochondrial activity, and in...
| Main Authors: | , |
|---|---|
| Other Authors: | , , |
| Format: | Article |
| Language: | English |
| Published: |
Society for Neuroscience,
2017-11-16T21:31:46Z.
|
| Subjects: | |
| Online Access: | Get fulltext |