BLISS is a versatile and quantitative method for genome-wide profiling of DNA double-strand breaks

BLISS is a versatile and quantitative method for genome-wide profiling of DNA double-strand breaks

Precisely measuring the location and frequency of DNA double-strand breaks (DSBs) along the genome is instrumental to understanding genomic fragility, but current methods are limited in versatility, sensitivity or practicality. Here we present Breaks Labeling In Situ and Sequencing (BLISS), featurin...

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Bibliographic Details
Main Authors: Mirzazadeh, Reza (Author), Garnerone, Silvano (Author), Schneider, Martin W. (Author), Kallas, Tomasz (Author), Custodio, Joaquin (Author), Wernersson, Erik (Author), Bienko, Magda (Author), Crosetto, Nicola (Author), Yan, Winston Xia (Contributor), Scott, David Arthur (Contributor), Li, Yinqing (Contributor), Gao, Linyi (Contributor), Federova, Yana (Contributor), Zetsche, Bernd (Contributor), Zhang, Feng (Contributor)
Other Authors: Harvard University- (Contributor), Massachusetts Institute of Technology. Department of Biological Engineering (Contributor), Massachusetts Institute of Technology. Department of Brain and Cognitive Sciences (Contributor), McGovern Institute for Brain Research at MIT (Contributor)
Format: Article
Language:English
Published: Nature Publishing Group, 2017-11-27T15:18:06Z.
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