Calcified plaque modification alters local drug delivery in the treatment of peripheral atherosclerosis

Calcified plaque modification alters local drug delivery in the treatment of peripheral atherosclerosis

Background: Calcific atherosclerosis is a major challenge to intraluminal drug delivery in peripheral artery disease (PAD). Objectives: We evaluated the effects of orbital atherectomy on intraluminal paclitaxel delivery to human peripheral arteries with substantial calcified plaque. Methods: Diagnos...

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Main Authors: Zani, Brett (Author), Stanley, James (Author), Muraj, Benny (Author), Knutson, Jennifer (Author), Kohler, Robert (Author), Markham, Peter (Author), Nikanorov, Alexander (Author), Tzafriri, A Rami (Contributor), Garcia Polite, Fernando (Contributor), Edelman, Elazer R (Contributor)
Other Authors: Massachusetts Institute of Technology. Institute for Medical Engineering & Science (Contributor), Harvard University- (Contributor)
Format: Article
Language:English
Published: Elsevier, 2017-12-14T16:56:46Z.
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