Genomic Correlates of Immune-Cell Infiltrates in Colorectal Carcinoma

Genomic Correlates of Immune-Cell Infiltrates in Colorectal Carcinoma

Large-scale genomic characterization of tumors from prospective cohort studies may yield new insights into cancer pathogenesis. We performed whole-exome sequencing of 619 incident colorectal cancers (CRCs) and integrated the results with tumor immunity, pathology, and survival data. We identified re...

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Main Authors: Giannakis, Marios (Author), Mu, Xinmeng Jasmine (Author), Shukla, Sachet A (Author), Qian, Zhi Rong (Author), Cohen, Ofir (Author), Nishihara, Reiko (Author), Bahl, Samira (Author), Cao, Yin (Author), Amin-Mansour, Ali (Author), Yamauchi, Mai (Author), Sukawa, Yasutaka (Author), Stewart, Chip (Author), Rosenberg, Mara (Author), Mima, Kosuke (Author), Inamura, Kentaro (Author), Nosho, Katsuhiko (Author), Nowak, Jonathan A (Author), Lawrence, Michael S (Author), Giovannucci, Edward L (Author), Chan, Andrew T (Author), Ng, Kimmie (Author), Meyerhardt, Jeffrey A (Author), Van Allen, Eliezer M (Author), Getz, Gad (Author), Gabriel, Stacey B (Author), Wu, Catherine J (Author), Fuchs, Charles S (Author), Ogino, Shuji (Author), Garraway, Levi A (Author), Lander, Eric Steven (Contributor)
Other Authors: Massachusetts Institute of Technology. Department of Biology (Contributor)
Format: Article
Language:English
Published: Elsevier, 2018-01-22T20:49:57Z.
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