Erythropoietin signaling regulates heme biosynthesis
Heme is required for survival of all cells, and in most eukaryotes, is produced through a series of eight enzymatic reactions. Although heme production is critical for many cellular processes, how it is coupled to cellular differentiation is unknown. Here, using zebrafish, murine, and human models,...
Main Authors: | Chung, Jacky (Author), Wittig, Johannes G (Author), Ghamari, Alireza (Author), Maeda, Manami (Author), Dailey, Tamara A (Author), Bergonia, Hector (Author), Kafina, Martin D (Author), Coughlin, Emma E (Author), Minogue, Catherine E (Author), Hebert, Alexander S (Author), Li, Liangtao (Author), Kaplan, Jerry (Author), Lodish, Harvey F (Contributor), Bauer, Daniel E (Author), Orkin, Stuart H (Author), Cantor, Alan B (Author), Maeda, Takahiro (Author), Phillips, John D (Author), Coon, Joshua J (Author), Pagliarini, David J (Author), Dailey, Harry A (Author), Paw, Barry H (Author) |
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Other Authors: | Massachusetts Institute of Technology. Department of Biology (Contributor), Whitehead Institute for Biomedical Research (Contributor) |
Format: | Article |
Language: | English |
Published: |
eLife Sciences Publications, Ltd,
2018-02-09T16:53:30Z.
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Subjects: | |
Online Access: | Get fulltext |
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