Oil Palm Phenolics Inhibit the n Vitro Aggregation of β-Amyloid Peptide into Oligomeric Complexes

Alzheimer's disease is a severe neurodegenerative disease characterized by the aggregation of amyloid-β peptide (Aβ) into toxic oligomers which activate microglia and astrocytes causing acute neuroinflammation. Multiple studies show that the soluble oligomers of Aβ42 are neurotoxic and proinfla...

Full description

Bibliographic Details
Main Authors: Tan, Yew Ai (Author), Sambanthamurthi, Ravigadevi (Author), Weinberg, Robert P (Contributor), Koledova, Vera V (Contributor), Shin, Alice Hyeari (Contributor), Park, Jennifer (Contributor), Sinskey, Anthony J (Contributor), Rha, Chokyun (Contributor)
Other Authors: Massachusetts Institute of Technology. Biomaterials Science and Engineering Laboratory (Contributor), Massachusetts Institute of Technology. Department of Biology (Contributor)
Format: Article
Language:English
Published: Hindawi Publishing Corporation, 2018-02-12T18:41:12Z.
Subjects:
Online Access:Get fulltext