Barcoded nanoparticles for high throughput in vivo discovery of targeted therapeutics

Barcoded nanoparticles for high throughput in vivo discovery of targeted therapeutics

Nucleic acid therapeutics are limited by inefficient delivery to target tissues and cells and by an incomplete understanding of how nanoparticle structure affects biodistribution to off-target organs. Although thousands of nanoparticle formulations have been designed to deliver nucleic acids, most n...

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Bibliographic Details
Main Authors: Kauffman, Kevin John (Contributor), Xing, Yiping (Contributor), Shaw, Taylor E. (Contributor), Mir, Faryal (Contributor), Dlott, Chloe C. (Contributor), Langer, Robert S (Contributor), Anderson, Daniel Griffith (Contributor), Wang, Eric T (Contributor), Dahlman, James E. (Author)
Other Authors: Massachusetts Institute of Technology. Institute for Medical Engineering & Science (Contributor), Harvard University- (Contributor), Massachusetts Institute of Technology. Department of Chemical Engineering (Contributor), Massachusetts Institute of Technology. Department of Electrical Engineering and Computer Science (Contributor), Koch Institute for Integrative Cancer Research at MIT (Contributor), Dahlman, James (Contributor)
Format: Article
Language:English
Published: National Academy of Sciences (U.S.), 2018-02-22T19:22:58Z.
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