PHF6 regulates phenotypic plasticity through chromatin organization within lineage-specific genes

PHF6 regulates phenotypic plasticity through chromatin organization within lineage-specific genes

Developmental and lineage plasticity have been observed in numerous malignancies and have been correlated with tumor progression and drug resistance. However, little is known about the molecular mechanisms that enable such plasticity to occur. Here, we describe the function of the plant homeodomain...

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Main Authors: Weintraub, Abraham S. (Author), Buenrostro, Jason D. (Author), Cheng, Christine S. (Author), Regev, Aviv (Author), Young, Richard A. (Author), Soto Feliciano, Yadira M. (Contributor), Bartlebaugh, Jordan M. E. (Contributor), Sanchez-Rivera, Francisco Javier (Contributor), Bhutkar, Arjun (Contributor), Jacks, Tyler E. (Contributor), Hemann, Michael (Contributor), Liu, Yunpeng,S.M.Massachusetts Institute of Technology (Author)
Other Authors: Massachusetts Institute of Technology. Department of Biology (Contributor), Koch Institute for Integrative Cancer Research at MIT (Contributor), Liu, Yunpeng (Contributor)
Format: Article
Language:English
Published: Cold Spring Harbor Laboratory Press, 2018-03-19T19:51:00Z.
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