SMC complexes differentially compact mitotic chromosomes according to genomic context

SMC complexes differentially compact mitotic chromosomes according to genomic context

Structural maintenance of chromosomes (SMC) protein complexes are key determinants of chromosome conformation. Using Hi-C and polymer modelling, we study how cohesin and condensin, two deeply conserved SMC complexes, organize chromosomes in the budding yeast Saccharomyces cerevisiae. The canonical r...

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Bibliographic Details
Main Authors: Schalbetter, Stephanie Andrea (Author), Belton, Jon-Matthew (Author), Miles, Catrina (Author), Yu, Miao (Author), Dekker, Job (Author), Baxter, Jonathan (Author), Goloborodko, Anton (Contributor), Fudenberg, Geoffrey (Contributor), Mirny, Leonid A (Contributor)
Other Authors: Institute for Medical Engineering and Science (Contributor), Massachusetts Institute of Technology. Department of Physics (Contributor)
Format: Article
Language:English
Published: Nature Publishing Group, 2018-04-20T20:04:56Z.
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