Thyroid hormone receptor beta and NCOA4 regulate terminal erythrocyte differentiation

Thyroid hormone receptor beta and NCOA4 regulate terminal erythrocyte differentiation

An effect of thyroid hormone (TH) on erythropoiesis has been known for more than a century but the molecular mechanism(s) by which TH affects red cell formation is still elusive. Here we demonstrate an essential role of TH during terminal human erythroid cell differentiation; specific depletion of T...

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Main Authors: Gao, Xiaofei (Author), Lee, Hsiang-Ying (Author), Li, Wenbo (Author), Barrasa, M. Inmaculada (Author), Ma, Qi (Author), Elmes, Russell R. (Author), Rosenfeld, Michael G. (Author), Platt, Randall Jeffrey (Contributor), Lodish, Harvey F (Contributor)
Other Authors: Massachusetts Institute of Technology. Department of Biological Engineering (Contributor), Massachusetts Institute of Technology. Department of Biology (Contributor)
Format: Article
Language:English
Published: National Academy of Sciences (U.S.), 2018-04-24T14:51:25Z.
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