Regulation of Peripheral Myelination through Transcriptional Buffering of Egr2 by an Antisense Long Non-coding RNA

Regulation of Peripheral Myelination through Transcriptional Buffering of Egr2 by an Antisense Long Non-coding RNA

Precise regulation of Egr2 transcription is fundamentally important to the control of peripheral myelination. Here, we describe a long non-coding RNA antisense to the promoter of Egr2 (Egr2-AS-RNA). During peripheral nerve injury, the expression of Egr2-AS-RNA is increased and correlates with decrea...

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Bibliographic Details
Main Authors: Martinez-Moreno, Margot (Author), Zepecki, John P. (Author), Olaru, Alexander (Author), Ness, Jennifer K. (Author), Tapinos, Nikos (Author), O'Shea, Timothy Mark (Contributor), Langer, Robert S (Contributor)
Other Authors: Massachusetts Institute of Technology. Institute for Medical Engineering & Science (Contributor), Koch Institute for Integrative Cancer Research at MIT (Contributor)
Format: Article
Language:English
Published: Elsevier, 2018-04-24T17:20:56Z.
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