Innate Lymphoid Cells Are Depleted Irreversibly during Acute HIV-1 Infection in the Absence of Viral Suppression

Innate Lymphoid Cells Are Depleted Irreversibly during Acute HIV-1 Infection in the Absence of Viral Suppression

Innate lymphoid cells (ILCs) play a central role in the response to infection by secreting cytokines crucial for immune regulation, tissue homeostasis, and repair. Although dysregulation of these systems is central to pathology, the impact of HIV-1 on ILCs remains unknown. We found that human blood...

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Main Authors: Kløverpris, Henrik N. (Author), Mjösberg, Jenny (Author), Mabuka, Jenniffer M. (Author), Wellmann, Amanda (Author), Ndhlovu, Zaza (Author), Yadon, Marisa C. (Author), Nhamoyebonde, Shepherd (Author), Muenchhoff, Maximilian (Author), Simoni, Yannick (Author), Andersson, Frank (Author), Kuhn, Warren (Author), Garrett, Nigel (Author), Burgers, Wendy A. (Author), Kamya, Philomena (Author), Pretorius, Karyn (Author), Dong, Krista (Author), Moodley, Amber (Author), Newell, Evan W. (Author), Kasprowicz, Victoria (Author), Abdool Karim, Salim S. (Author), Goulder, Philip (Author), Walker, Bruce D. (Author), Ndung'u, Thumbi (Author), Leslie, Alasdair (Author), Kazer, Samuel Weisgurt (Contributor), Shalek, Alexander K (Contributor)
Other Authors: Institute for Medical Engineering and Science (Contributor), Massachusetts Institute of Technology. Department of Chemistry (Contributor), Shalek, Alex K. (Contributor)
Format: Article
Language:English
Published: Elsevier, 2018-04-24T19:09:04Z.
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