Cellular normoxic biophysical markers of hydroxyurea treatment in sickle cell disease

Cellular normoxic biophysical markers of hydroxyurea treatment in sickle cell disease

Hydroxyurea (HU) has been used clinically to reduce the frequency of painful crisis and the need for blood transfusion in sickle cell disease (SCD) patients. However, the mechanisms underlying such beneficial effects of HU treatment are still not fully understood. Studies have indicated a weak corre...

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Main Authors: Hosseini, Poorya (Contributor), Abidi, Sabia Z. (Author), Du, E (Author), Papageorgiou, Dimitrios P. (Contributor), Choi, Youngwoon (Author), Higgins, John M. (Author), Kato, Gregory J. (Author), Suresh, Subra (Author), Dao, Ming (Contributor), Yaqoob, Zahid (Contributor), So, Peter T. C. (Contributor), Park, YongKeun, Ph.D. Massachusetts Institute of Technology (Author)
Other Authors: Massachusetts Institute of Technology. Department of Biological Engineering (Contributor), Massachusetts Institute of Technology. Department of Materials Science and Engineering (Contributor), Massachusetts Institute of Technology. Department of Mechanical Engineering (Contributor), Massachusetts Institute of Technology. Laser Biomedical Research Center (Contributor)
Format: Article
Language:English
Published: National Academy of Sciences (U.S.), 2018-04-26T20:21:07Z.
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