RCK: accurate and efficient inference of sequence- and structure-based protein-RNA binding models from RNAcompete data

RCK: accurate and efficient inference of sequence- and structure-based protein-RNA binding models from RNAcompete data

Motivation: Protein-RNA interactions, which play vital roles in many processes, are mediated through both RNA sequence and structure. CLIP-based methods, which measure protein-RNA binding in vivo, suffer from experimental noise and systematic biases, whereas in vitro experiments capture a clearer si...

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Bibliographic Details
Main Authors: Orenstein, Yaron (Contributor), Wang, Yuhao (Contributor), Berger Leighton, Bonnie (Contributor)
Other Authors: Massachusetts Institute of Technology. Computer Science and Artificial Intelligence Laboratory (Contributor), Massachusetts Institute of Technology. Department of Electrical Engineering and Computer Science (Contributor), Massachusetts Institute of Technology. Department of Mathematics (Contributor)
Format: Article
Language:English
Published: Oxford University Press (OUP), 2018-05-23T17:12:48Z.
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