New Insights into the Troubles of Aneuploidy

Deviation from a balanced genome by either gain or loss of entire chromosomes is generally tolerated poorly in all eukaryotic systems studied to date. Errors in mitotic or meiotic cell division lead to aneuploidy, which places a burden of additional or insufficient gene products from the missegregat...

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Bibliographic Details
Main Authors: Siegel, Jacob (Contributor), Amon, Angelika B. (Contributor)
Other Authors: Koch Institute for Integrative Cancer Research at MIT (Contributor)
Format: Article
Language:English
Published: Annual Reviews, 2018-06-05T18:41:02Z.
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