The Menu of Features that Define Primary MicroRNAs and Enable De Novo Design of MicroRNA Genes
MicroRNAs (miRNAs) are small regulatory RNAs processed from stem-loop regions of primary transcripts (pri-miRNAs), with the choice of stem loops for initial processing largely determining what becomes a miRNA. To identify sequence and structural features influencing this choice, we determined cleava...
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| Format: | Article |
| Language: | English |
| Published: |
Elsevier BV,
2018-06-15T13:25:26Z.
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| Subjects: | |
| Online Access: | Get fulltext |