Metabolic control of primed human pluripotent stem cell fate and function by the miR-200c-SIRT2 axis
A hallmark of cancer cells is the metabolic switch from oxidative phosphorylation (OXPHOS) to glycolysis, a phenomenon referred to as the 'Warburg effect', which is also observed in primed human pluripotent stem cells (hPSCs). Here, we report that downregulation of SIRT2 and upregulation o...
Main Authors: | , , , , , , , , , , , , , |
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Other Authors: | , , |
Format: | Article |
Language: | English |
Published: |
Nature Publishing Group,
2018-06-19T14:18:01Z.
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Subjects: | |
Online Access: | Get fulltext |