The influence of microRNAs and poly(A) tail length on endogenous mRNA-protein complexes

The influence of microRNAs and poly(A) tail length on endogenous mRNA-protein complexes

Background: All mRNAs are bound in vivo by proteins to form mRNA-protein complexes (mRNPs), but changes in the composition of mRNPs during posttranscriptional regulation remain largely unexplored. Here, we have analyzed, on a transcriptome-wide scale, how microRNA-mediated repression modulates the a...

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Main Authors: Wang, Miranda (Author), Lugowski, Andrew (Author), Nicholson, Beth (Author), Laver, John D. (Author), Sidhu, Sachdev S. (Author), Smibert, Craig A. (Author), Lipshitz, Howard D. (Author), Subtelny, Alexander Orest (Contributor), Rissland, Olivia S. (Contributor), Bartel, David (Contributor)
Other Authors: Massachusetts Institute of Technology. Department of Biology (Contributor), Whitehead Institute for Biomedical Research (Contributor)
Format: Article
Language:English
Published: Biomed Central Ltd., 2018-06-21T13:41:48Z.
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