The Next Generation of Orthotopic Thyroid Cancer Models: Immunocompetent Orthotopic Mouse Models of BRAF

Background: While the development of new treatments for aggressive thyroid cancer has advanced in the last 10 years, progress has trailed headways made with other malignancies. A lack of reliable authenticated human cell lines and reproducible animal models is one major roadblock to preclinical test...

Full description

Bibliographic Details
Main Authors: Vanden Borre, Pierre (Author), McFadden, David G. (Author), Gunda, Viswanath (Author), Sadow, Peter M. (Author), Varmeh, Shohreh (Author), Bernasconi, Maria (Author), Parangi, Sareh (Author), Jacks, Tyler E. (Contributor)
Other Authors: Massachusetts Institute of Technology. Department of Biology (Contributor), Koch Institute for Integrative Cancer Research at MIT (Contributor)
Format: Article
Language:English
Published: Mary Ann Liebert Inc, 2018-06-25T18:08:02Z.
Subjects:
Online Access:Get fulltext