Transcription elongation factors represent in vivo cancer dependencies in glioblastoma

Transcription elongation factors represent in vivo cancer dependencies in glioblastoma

Glioblastoma is a universally lethal cancer with a median survival time of approximately 15 months. Despite substantial efforts to define druggable targets, there are no therapeutic options that notably extend the lifespan of patients with glioblastoma. While previous work has largely focused on in...

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Main Authors: Miller, Tyler E. (Author), Liau, Brian B. (Author), Wallace, Lisa C. (Author), Morton, Andrew R. (Author), Xie, Qi (Author), Dixit, Deobrat (Author), Factor, Daniel C. (Author), Kim, Leo J. Y. (Author), Morrow, James J. (Author), Wu, Qiulian (Author), Mack, Stephen C. (Author), Hubert, Christopher G. (Author), Gillespie, Shawn M. (Author), Flavahan, William A. (Author), Hoffmann, Thomas (Author), Thummalapalli, Rohit (Author), Paddison, Patrick J. (Author), Horbinski, Craig M. (Author), Zuber, Johannes (Author), Scacheri, Peter C. (Author), Bernstein, Bradley E. (Author), Tesar, Paul J. (Author), Rich, Jeremy N. (Author), Hemann, Michael (Contributor)
Other Authors: Massachusetts Institute of Technology. Department of Biology (Contributor)
Format: Article
Language:English
Published: Springer Nature, 2018-06-26T17:25:27Z.
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