The neuropeptide NMU amplifies ILC2-driven allergic lung inflammation

The neuropeptide NMU amplifies ILC2-driven allergic lung inflammation

Type 2 innate lymphoid cells (ILC2s) both contribute to mucosal homeostasis and initiate pathologic inflammation in allergic asthma. However, the signals that direct ILC2s to promote homeostasis versus inflammation are unclear. To identify such molecular cues, we profiled mouse lung-resident ILCs us...

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Main Authors: Wallrapp, Antonia (Author), Riesenfeld, Samantha J. (Author), Burkett, Patrick R. (Author), Abdulnour, Raja-Elie E. (Author), Nyman, Jackson (Author), Dionne, Danielle (Author), Hofree, Matan (Author), Cuoco, Michael S. (Author), Rodman, Christopher (Author), Farouq, Daneyal (Author), Haas, Brian J. (Author), Tickle, Timothy L. (Author), Trombetta, John J. (Author), Baral, Pankaj (Author), Klose, Christoph S. N. (Author), Mahlakõiv, Tanel (Author), Artis, David (Author), Rozenblatt-Rosen, Orit (Author), Chiu, Isaac M. (Author), Levy, Bruce D. (Author), Kowalczyk, Monika S. (Author), Regev, Aviv (Contributor), Kuchroo, Vijay K. (Author)
Other Authors: Massachusetts Institute of Technology. Department of Biology (Contributor), Koch Institute for Integrative Cancer Research at MIT (Contributor)
Format: Article
Language:English
Published: Nature Publishing Group, 2018-07-05T14:50:24Z.
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