Single-cell RNA-seq reveals new types of human blood dendritic cells, monocytes, and progenitors

Single-cell RNA-seq reveals new types of human blood dendritic cells, monocytes, and progenitors

Dendritic cells (DCs) and monocytes play a central role in pathogen sensing, phagocytosis, and antigen presentation and consist of multiple specialized subtypes. However, their identities and interrelationships are not fully understood. Using unbiased single-cell RNA sequencing (RNA-seq) of ~2400 ce...

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Main Authors: Villani, Alexandra-Chloé (Author), Satija, Rahul (Author), Reynolds, Gary (Author), Sarkizova, Siranush (Author), Shekhar, Karthik (Author), Fletcher, James (Author), Griesbeck, Morgane (Author), Butler, Andrew (Author), Zheng, Shiwei (Author), Lazo, Suzan (Author), Jardine, Laura (Author), Dixon, David (Author), Stephenson, Emily (Author), Nilsson, Emil (Author), Grundberg, Ida (Author), McDonald, David (Author), Filby, Andrew (Author), Li, Weibo (Author), De Jager, Philip L. (Author), Rozenblatt-Rosen, Orit (Author), Lane, Andrew A. (Author), Haniffa, Muzlifah (Author), Regev, Aviv (Contributor), Hacohen, Nir (Author)
Other Authors: Massachusetts Institute of Technology. Department of Biology (Contributor), Koch Institute for Integrative Cancer Research at MIT (Contributor)
Format: Article
Language:English
Published: American Association for the Advancement of Science (AAAS), 2018-07-05T14:56:01Z.
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