A System to Study Aneuploidy In Vivo

Aneuploidy, an imbalanced chromosome number, is associated with both cancer and developmental disorders such as Down syndrome (DS). To determine how aneuploidy affects cellular and organismal physiology, we have developed a system to evaluate aneuploid cell fitness in vivo. By transplanting hematopo...

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Bibliographic Details
Main Authors: Pfau, Sarah Jeanne (Contributor), Amon, Angelika B (Contributor)
Other Authors: Massachusetts Institute of Technology. Department of Biology (Contributor), Koch Institute for Integrative Cancer Research at MIT (Contributor)
Format: Article
Language:English
Published: Cold Spring Harbor Laboratory, 2018-07-06T18:02:08Z.
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