Super-Enhancer-Mediated RNA Processing Revealed by Integrative MicroRNA Network Analysis

Super-Enhancer-Mediated RNA Processing Revealed by Integrative MicroRNA Network Analysis

Super-enhancers are an emerging subclass of regulatory regions controlling cell identity and disease genes. However, their biological function and impact on miRNA networks are unclear. Here, we report that super-enhancers drive the biogenesis of master miRNAs crucial for cell identity by enhancing b...

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Bibliographic Details
Main Authors: Suzuki, Hiroshi (Contributor), Young, Richard A. (Author), Sharp, Phillip A. (Author)
Other Authors: Massachusetts Institute of Technology. Department of Biology (Contributor), Koch Institute for Integrative Cancer Research at MIT (Contributor), Young, Richard A (Contributor), Sharp, Phillip A (Contributor)
Format: Article
Language:English
Published: Elsevier, 2018-07-10T14:44:20Z.
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