Amino Acids Rather than Glucose Account for the Majority of Cell Mass in Proliferating Mammalian Cells

Amino Acids Rather than Glucose Account for the Majority of Cell Mass in Proliferating Mammalian Cells

Cells must duplicate their mass in order to proliferate. Glucose and glutamine are the major nutrients consumed by proliferating mammalian cells, but the extent to which these and other nutrients contribute to cell mass is unknown. We quantified the fraction of cell mass derived from different nutri...

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Bibliographic Details
Main Authors: Johnson, Marc O (Author), Rathmell, Jeffrey C (Author), Steinhauser, Matthew L (Author), Hosios, Aaron Marc (Contributor), Hecht, Vivian Chaya (Contributor), Danai, Laura V (Contributor), Manalis, Scott R (Contributor), Vander Heiden, Matthew G. (Contributor)
Other Authors: Massachusetts Institute of Technology. Department of Biological Engineering (Contributor), Massachusetts Institute of Technology. Department of Biology (Contributor), Koch Institute for Integrative Cancer Research at MIT (Contributor)
Format: Article
Language:English
Published: Elsevier BV, 2018-07-11T20:39:17Z.
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