A breast cancer stem cell niche supported by juxtacrine signalling from monocytes and macrophages

A breast cancer stem cell niche supported by juxtacrine signalling from monocytes and macrophages

The cell-biological program termed the epithelial-mesenchymal transition (EMT) confers on cancer cells mesenchymal traits and an ability to enter the cancer stem cell (CSC) state. However, the interactions between CSCs and their surrounding microenvironment are poorly understood. Here we show that t...

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Bibliographic Details
Main Authors: Clauser, Karl R. (Author), Fröse, Julia (Author), Ye, Xin (Author), Eaton, Elinor Ng (Author), Reinhardt, Ferenc (Author), Donnenberg, Vera S. (Author), Bhargava, Rohit (Author), Carr, Steven A. (Author), Lu, Haihui (Contributor), Tam, Wai Leong (Contributor), Weinberg, Robert A (Contributor)
Other Authors: Massachusetts Institute of Technology. Department of Biology (Contributor), Ludwig Center for Molecular Oncology (Massachusetts Institute of Technology) (Contributor)
Format: Article
Language:English
Published: Springer Nature, 2018-07-12T19:16:53Z.
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