EMT, CSCs, and drug resistance: the mechanistic link and clinical implications
The success of anticancer therapy is usually limited by the development of drug resistance. Such acquired resistance is driven, in part, by intratumoural heterogeneity-that is, the phenotypic diversity of cancer cells co-inhabiting a single tumour mass. The introduction of the cancer stem cell (CSC)...
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Format: | Article |
Language: | English |
Published: |
Nature Publishing Group,
2018-07-13T13:36:55Z.
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Online Access: | Get fulltext |