How Does Multistep Tumorigenesis Really Proceed?

Identifying the cancer cells-of-origin is of great interest, as it holds the potential to elucidate biologic mechanisms inherent in the normal cell state that have been co-opted to drive the oncogenic cell state. An emerging concept, proposed here, states that cancer stem cells, key players in cance...

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Bibliographic Details
Main Authors: Chaffer, Christine L. (Contributor), Weinberg, Robert A (Contributor)
Other Authors: Massachusetts Institute of Technology. Department of Biology (Contributor)
Format: Article
Language:English
Published: American Association for Cancer Research (AACR), 2018-07-13T14:58:25Z.
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