The DNA-sensing AIM2 inflammasome controls radiation-induced cell death and tissue injury

The DNA-sensing AIM2 inflammasome controls radiation-induced cell death and tissue injury

Acute exposure to ionizing radiation induces massive cell death and severe damage to tissues containing actively proliferating cells, including bone marrow and the gastrointestinal tract. However, the cellular and molecular mechanisms underlying this pathology remain controversial. Here, we show tha...

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Bibliographic Details
Main Authors: Hu, Bo (Author), Jin, Chengcheng (Author), Li, Hua-Bing (Author), Tong, Jiyu (Author), Ouyang, Xinshou (Author), Zhu, Shu (Author), Strowig, Till (Author), Zhao, Chen (Author), Henao-Mejia, Jorge (Author), Fitzgerald, Katherine A. (Author), Eisenbarth, Stephanie C. (Author), Elinav, Eran (Author), Flavell, Richard A. (Author), Cetinbas, Naniye (Contributor), Lam, Fred Chiu-Lai (Contributor), Yilmaz, Omer (Contributor)
Other Authors: Koch Institute for Integrative Cancer Research at MIT (Contributor)
Format: Article
Language:English
Published: American Association for the Advancement of Science (AAAS), 2018-07-23T18:45:54Z.
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