Short- and long-term effects of chromosome mis-segregation and aneuploidy

Dividing cells that experience chromosome mis-segregation generate aneuploid daughter cells, which contain an incorrect number of chromosomes. Although aneuploidy interferes with the proliferation of untransformed cells, it is also, paradoxically, a hallmark of cancer, a disease defined by increased...

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Bibliographic Details
Main Authors: Santaguida, Stefano (Contributor), Amon, Angelika B (Contributor)
Other Authors: Massachusetts Institute of Technology. Department of Biology (Contributor), Koch Institute for Integrative Cancer Research at MIT (Contributor), Amon A (Contributor)
Format: Article
Language:English
Published: Nature Publishing Group, 2018-07-30T18:15:42Z.
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