Short- and long-term effects of chromosome mis-segregation and aneuploidy
Dividing cells that experience chromosome mis-segregation generate aneuploid daughter cells, which contain an incorrect number of chromosomes. Although aneuploidy interferes with the proliferation of untransformed cells, it is also, paradoxically, a hallmark of cancer, a disease defined by increased...
Main Authors: | Santaguida, Stefano (Contributor), Amon, Angelika B (Contributor) |
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Other Authors: | Massachusetts Institute of Technology. Department of Biology (Contributor), Koch Institute for Integrative Cancer Research at MIT (Contributor), Amon A (Contributor) |
Format: | Article |
Language: | English |
Published: |
Nature Publishing Group,
2018-07-30T18:15:42Z.
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Subjects: | |
Online Access: | Get fulltext |
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