Recurrent and functional regulatory mutations in breast cancer

Recurrent and functional regulatory mutations in breast cancer

Genomic analysis of tumours has led to the identification of hundreds of cancer genes on the basis of the presence of mutations in protein-coding regions. By contrast, much less is known about cancer-causing mutations in non-coding regions. Here we perform deep sequencing in 360 primary breast cance...

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Main Authors: Parasuraman, Prasanna (Author), Tiao, Grace (Author), Kim, Jaegil (Author), Taylor-Weiner, Amaro (Author), Rodriguez-Cuevas, Sergio (Author), Rosenberg, Mara (Author), Hess, Julian (Author), Stewart, Chip (Author), Maruvka, Yosef E. (Author), Stojanov, Petar (Author), Seepo, Sara (Author), Cibulskis, Carrie (Author), Tracy, Adam (Author), Pugh, Trevor J. (Author), Lee, Jesse (Author), Zheng, Zongli (Author), Ellisen, Leif W. (Author), Iafrate, A. John (Author), Boehm, Jesse S. (Author), Baselga, Jose (Author), Hidalgo-Miranda, Alfredo (Author), Shioda, Toshi (Author), Bernards, Andre (Author), Engreitz, Jesse Michael (Contributor), Lander, Eric Steven (Contributor), Rheinbay, Esther (Contributor), Lawrence, Michael (Contributor), Cortes, Maria (Contributor), Gabriel, Stacey (Contributor), Golub, Todd (Contributor), Getz, Gad Asher (Contributor), Meyerson, Matthew L. (Author)
Other Authors: Broad Institute of MIT and Harvard (Contributor), Harvard University- (Contributor), Massachusetts Institute of Technology. Department of Biology (Contributor), Meyerson, Matthew L (Contributor)
Format: Article
Language:English
Published: Nature Publishing Group, 2018-08-06T16:05:22Z.
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