Multiscale characterization of the mineral phase at skeletal sites of breast cancer metastasis

Multiscale characterization of the mineral phase at skeletal sites of breast cancer metastasis

Skeletal metastases, the leading cause of death in advanced breast cancer patients, depend on tumor cell interactions with the mineralized bone extracellular matrix. Bone mineral is largely composed of hydroxyapatite (HA) nanocrystals with physicochemical properties that vary significantly by anatom...

Full description

Bibliographic Details
Main Authors: He, Frank (Author), Chiou, Aaron E. (Author), Loh, Hyun Chae (Contributor), Lynch, Maureen (Author), Seo, Bo Ri (Author), Song, Young Hye (Author), Lee, Min Joon (Author), Hoerth, Rebecca (Author), Bortel, Emely L. (Author), Willie, Bettina M. (Author), Duda, Georg N. (Author), Estroff, Lara A. (Author), Masic, Admir (Contributor), Wagermaier, Wolfgang (Author), Fratzl, Peter (Author), Fischbach, Claudia (Author)
Other Authors: Massachusetts Institute of Technology. Department of Civil and Environmental Engineering (Contributor)
Format: Article
Language:English
Published: National Academy of Sciences (U.S.), 2018-08-20T13:39:41Z.
Subjects:
Article
Online Access:Get fulltext

Internet

Get fulltext

Similar Items