A Blueprint for a Synthetic Genetic Feedback Controller to Reprogram Cell Fate
To artificially reprogram cell fate, experimentalists manipulate the gene regulatory networks (GRNs) that maintain a cell's phenotype. In practice, reprogramming is often performed by constant overexpression of specific transcription factors (TFs). This process can be unreliable and inefficient...
Main Authors: | , , , |
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Other Authors: | , , , , |
Format: | Article |
Language: | English |
Published: |
Elsevier,
2018-08-28T15:05:06Z.
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Subjects: | |
Online Access: | Get fulltext |