Carbon Sources Tune Antibiotic Susceptibility in Pseudomonas aeruginosa via Tricarboxylic Acid Cycle Control

Carbon Sources Tune Antibiotic Susceptibility in Pseudomonas aeruginosa via Tricarboxylic Acid Cycle Control

Metabolically dormant bacteria present a critical challenge to effective antimicrobial therapy because these bacteria are genetically susceptible to antibiotic treatment but phenotypically tolerant. Such tolerance has been attributed to impaired drug uptake, which can be reversed by metabolic stimul...

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Bibliographic Details
Main Authors: Belenky, Peter (Author), Park, Jihye (Author), Kim, Sun H. (Author), Moskowitz, Samuel M. (Author), Meylan, Sylvain (Contributor), Porter, Caroline (Contributor), Yang, Jason Hung-Ying (Contributor), Gutierrez, Arnaud (Contributor), Lobritz, Michael Andrew (Contributor), Collins, James J. (Contributor)
Other Authors: Institute for Medical Engineering and Science (Contributor), Massachusetts Institute of Technology. Department of Biological Engineering (Contributor)
Format: Article
Language:English
Published: Elsevier BV, 2018-08-28T16:04:49Z.
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