Recombinant cells in the lung increase with age via de novo recombination events and clonal expansion

Homologous recombination (HR) is a critical DNA repair pathway, which is usually error-free, but can sometimes lead to cancer-promoting mutations. Despite the importance of HR as a driver of mutations, the spontaneous frequency of such mutations has proven difficult to study. To gain insight to loca...

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Bibliographic Details
Main Authors: Li, Na (Author), Kimoto, Takafumi (Contributor), Kay, Jennifer Elizabeth (Contributor), Engelward, Bevin P (Contributor)
Other Authors: Massachusetts Institute of Technology. Department of Biological Engineering (Contributor)
Format: Article
Language:English
Published: Wiley Blackwell, 2018-09-06T14:43:21Z.
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