Recombinant cells in the lung increase with age via de novo recombination events and clonal expansion
Homologous recombination (HR) is a critical DNA repair pathway, which is usually error-free, but can sometimes lead to cancer-promoting mutations. Despite the importance of HR as a driver of mutations, the spontaneous frequency of such mutations has proven difficult to study. To gain insight to loca...
Main Authors: | , , , |
---|---|
Other Authors: | |
Format: | Article |
Language: | English |
Published: |
Wiley Blackwell,
2018-09-06T14:43:21Z.
|
Subjects: | |
Online Access: | Get fulltext |