Isthmus Stem Cells Are the Origins of Metaplasia in the Gastric Corpus
The acquisition of genetic/epigenetic mutations in long-lived gastrointestinal stem cells leads to the development of cancer, as well as precancerous lesions such as metaplasia and dysplasia. In the proximal stomach corpus, this model of progression from stem cells has been supported by studies in m...
Main Authors: | , , |
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Format: | Article |
Language: | English |
Published: |
Elsevier BV,
2018-09-07T16:06:16Z.
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Online Access: | Get fulltext |